Improving Accuracy of Quantitative Susceptibility Mapping Using Edge-Weighted L1 Regularisation
Meng-Chi Hsieh 1,2 , Chung-Ming Chen 3 , Kun-Hsien Chou 4 , Ai-Ling Hsu 1,2 , Ching-Po Lin 4 , and Jyh-Horng Chen 1,2
Graduate Institute of Biomedical Electronics
and Bioinformatics, National Taiwan University, Taipei,
MRI/MRS Laboratory, Department of Electrical
Engineering, National Taiwan University, Taipei, Taiwan,
of Biomedical Engineering, National Taiwan University,
Connectivity Lab, Institute of Neuroscience, National
Yang-Ming University, Taipei, Taiwan
The purpose of this study is to improve accuracy for
quantitative susceptibility map (QSM) by Edge-Weighted
L1 (EW-L1) regularization. Numerical simulation and
human brain experiment were performed to demonstrate the
superiority of EW-L1 over conventional L1 method. Our
results showed that EW-L1 provides highly accurate
estimation and suppressed streaking artefact of QSM.
Preliminary results of brain imaging suggested its
feasibility of QSM in clinical practice.
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