Enhancing Image Contrast in Human Brain by Voxel Spread Function Method

Gibbs ringing artifacts especially pronounced in the presence of magnetic field inhomogeneities adversely affect different aspects of MRI. In quantitative MRI they bias and often corrupt measurements. The VSF (voxel spread function) method provides a platform for correcting images and can be applied to a variety of quantitative gradient-echo-based MRI techniques. Elimination of Gibbs artifacts in VSF approach requires solution of high-rank matrix equation (VSF equation) and relies on certain approximations. Herein we propose a method for solution of VSF equation allowing for substantially improving visibility of sharp edges and demonstrate improved contrast of blood vessels in the human brain.

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