Abstract #3223
MOBILE allows a follow-up of brain oxygen variations during a 100% 02 breathing
Florence Colliez 1 , Julie Magat 1 , Marta M Safronova 2 , Bndicte F Jordan 1 , Thierry Duprez 3 , and Bernard Gallez 1
1
Louvain Drug Research Institute, Biomedical
Magnetic Resonance Research Group, University of
Louvain, Brussels, Belgium,
2
Service
de Radiologie, Cliniques universitaires Saint-Luc,
Brussels, Belgium,
3
Department
of Radiology and Medical Imaging, Cliniques
universitaires Saint-Luc, Brussels, Belgium
There is a critical need for dynamic and noninvasive
methods able to monitor brain oxygenation in clinical
practice. Variations in T1 and T2* are potentially
valuable MRI tools to detect changes in tumor
oxygenation. We hereby (i) test the ability of MOBILE,
a method of oxygenation mapping based on the changes in
the relaxation properties of the tissue lipids, to map
brain oxygenation in brain and cerebellum (ii) evaluate
its capability to follow an increase in oxygenation on
healthy volunteers submitted to a 100% O2 breathing
(iii) and compare sensitivities of the MOBILE and
Oxygen enhanced MRI techniques.
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