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Abstract #3234

Tissue characterization of Gliomas: Initial clinical experience with Magnetic Resonance Fingerprinting (MRF)

Chaitra Badve 1 , Dan Ma 2 , Yun Jiang 2 , Alice Yu 3 , Jeffrey Sunshine 1 , Vikas Gulani 1,2 , and Mark Griswold 1,2

1 Radiology, Case Western Reserve University and University Hospitals Cleveland, Cleveland, Ohio, United States, 2 Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States, 3 School of Medicine, Case Western Reserve University, Cleveland, Ohio, United States

This study applies magnetic resonance fingerprinting for quantitative analysis of gliomas. Five glioma patients were scanned. T1, T2 quantification of solid tumor parenchyma and white matter at various locations was performed. T1, T2 values of tumor were significantly different than contralateral white matter. T1, T2 values of tumor were significantly different than perilesional white matter. These results demonstrate that quantitative analysis with MRF can distinguish glial tumors from peritumoral white matter changes and uninvolved white matter. MRF may also help to identify regions of infiltrative peritumoral edema in higher-grade tumors.

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