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Abstract #3240

3D Bio-Anatomical Imaging with High Isotropic Resolution for Musculoskeletal Applications

Weitian Chen 1 , Edwin Oei 2,3 , and Garry E Gold 2,4

1 Global MR Applications & Workflow, GE Healthcare, Menlo Park, CA, United States, 2 Radiology, Stanford University, CA, United States, 3 Radiology, Erasmus MC Rotterdam, Netherlands, 4 Bioengineering and Orthopedic Surgery, Stanford University, CA, United States

Intermediate T2-weighted and PD-weighted FSE images are commonly used in clinical MRI for detection of joint abnormalities. There are increasing interests in using T2 and T1rho as biomarkers for improved diagnosis of osteoarthritis and related diseases. T2 or T1rho relaxometry is typically performed in 2D or 3D plane with inferior resolution compared to anatomical imaging due to scan time limitations. In this work, we investigated the use of a single scan to acquire T2-weighted, PD-weighted anatomy images and relaxometry map with 3D isotropic resolution of 0.6mm in a clinically feasible scan time. Both relaxometry map and anatomical images can be subsequently reformatted to arbitrary plane for post-analysis and diagnosis.

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