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Abstract #3245

The effect of echo time sampling on B0 field map estimation for QSM of liver iron overload

Samir D. Sharma 1 , Diego Hernando 1 , and Scott B. Reeder 1,2

1 Radiology, University of Wisconsin - Madison, Madison, WI, United States, 2 Medical Physics, University of Wisconsin - Madison, Madison, Wisconsin, United States

Precise estimation of the B0 field map is a critical component of quantitative susceptibility mapping (QSM). Using QSM, it may be possible to estimate the liver iron concentration (LIC) from the B0 field map. However, in order for this B0-based measurement of LIC to be precise (i.e. have low standard deviation), the estimate of the B0 field itself must be precise. In this work, we have analyzed the theoretical effects of the echo time sampling on the precision of the B0 field map estimate, and further, translated these results into precision limits of the LIC estimate.

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