Abstract #3283
Fast 2D Harmonic Filtering of MRI phase; application to discriminating cerebral microbleeds in a multicenter clinical dataset
Takoua Kaaouana 1,2 , Ludovic de Rochefort 3 , Thomas Samaille 1,2 , Nathalie Thierry 4 , Genevieve Chene 4 , Christine Delmaire 5 , Didier Dormont 6 , and Marie Chupin 1
1
CRICM, UPMC UMR_S975, INSERM U975, CNRS
UMR7225, ICM, INRIA, Paris, France,
2
CATI,
Paris, France,
3
Univ.
Paris-Sud, CNRS IR4M UMR8081, Orsay, France,
4
U897,
INSERM, Bordeaux, France,
5
Neuroradiology,
CHRU Roger Salengro, Lille, France,
6
Neuroradiology,
CHRU pitie salpetriere, Paris, France
In MRI signal, phase is proportional to the local
resonance frequency and therefore directly reflects
magnetic field changes induced by local magnetic
susceptibility sources. Composed of hemosiderin,
cerebral microbleed can act as susceptibility sources
and generate local dipole magnetic field. Here, we
introduce a physically motivated fast 2D phase
processing technique including unwrapping and harmonic
filtering which yields the internal field. We
demonstrate its applicability and robustness on
multicenter 2D datasets acquired in standardized
clinical setting to discriminate cerebral microbleeds.
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