A Standard MRI Approach to Assess High-Grade Glioma Response: Review the Essentials and Pitfalls of RANO Criteria

The evaluation of treatment in high-grade gliomas frequently relies on the radiographic response rate or progression-free survival. Neuroradiologists and neuro-oncologists do not use Response Assessment in Neuro-Oncology (RANO) criteria as part of their daily clinical practice. This can cause variability of understanding and application of the criteria, even misinterpret for disease progression and leads to discordance between central and local assessments for multicenter trials. Therefore, it is critical for trial clinicians and radiologists to understand the essentials of this standard approach. In this educational e-poster, the essential RANO guidelines, summarize important rules and discuss common pitfalls along with imaging examples were reviewed.

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