Meeting Banner
Abstract #3352

The Effect of Intravenous Gadolinium on Diffusion Kurtosis Imaging: Evaluation of Brain Tumors

Masaki Katsura 1,2 , Yuichi Suzuki 2 , Junichi Hata 2 , Hiroki Sasaki 1 , Harushi Mori 1 , Akira Kunimatsu 1 , Jian Xu 3 , Katsuya Maruyama 4 , and Kuni Ohtomo 1

1 Radiology, Graduate School of Medicine, The University of Tokyo, Bunkyo, Tokyo, Japan, 2 Radiology, The University of Tokyo Hospital, Bunkyo, Tokyo, Japan, 3 Siemens Healthcare USA, New York, United States, 4 Siemens Healthcare Japan, Tokyo, Japan

Diffusional kurtosis imaging (DKI) characterizes non-Gaussian water diffusion behavior. The principal metric derived from DKI is mean kurtosis (Kmean), which is thought to be an index of microstructural complexity. In the current study on clinical cases with brain tumors, Kmean did not change significantly after administration of gadolinium-based contrast material. Our results indicate that DKI can be repeated after gadolinium-enhanced MR studies. Therefore, when motion is detected on the initial DK scan or when repeated DKI images with different imaging techniques are needed, they can be performed after gadolinium-enhanced imaging without a significant change in Kmean.

This abstract and the presentation materials are available to members only; a login is required.

Join Here