How Important is the Effect of Lesion In-painting on Regional Atrophy in Multiple Sclerosis?
Sushmita Datta 1 , Terrell D. Staewen 1 , Stacy S. Cofield 2 , Gary R. Cutter 2 , Fred D. Lublin 3 , Jerry S. Wolinsky 4 , and Ponnada A. Narayana 1
Diagnostic and Interventional Imaging, The
University of Texas Health Science Center at Houston,
Houston, TX, United States,
University of Alabama at Birmingham, Birmingham,
Alabama, United States,
Corinne Goldsmith Dickinson Center for Multiple
Sclerosis, Mount Sinai School of Medicine, New York
City, New York, United States,
The University of Texas Health Science Center, Houston,
TX, United States
The effect of lesion in-painting on the estimated
regional atrophy in multiple sclerosis (MS) was
evaluated on a large cohort for different T2 lesion
burdens. The results suggest that in-painting has
effects on regions close to the ventricular regions. The
effect is most prominent at high lesion burden.
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