Abstract #3402
How Important is the Effect of Lesion In-painting on Regional Atrophy in Multiple Sclerosis?
Sushmita Datta 1 , Terrell D. Staewen 1 , Stacy S. Cofield 2 , Gary R. Cutter 2 , Fred D. Lublin 3 , Jerry S. Wolinsky 4 , and Ponnada A. Narayana 1
1
Diagnostic and Interventional Imaging, The
University of Texas Health Science Center at Houston,
Houston, TX, United States,
2
Biostatistics,
University of Alabama at Birmingham, Birmingham,
Alabama, United States,
3
The
Corinne Goldsmith Dickinson Center for Multiple
Sclerosis, Mount Sinai School of Medicine, New York
City, New York, United States,
4
Neurology,
The University of Texas Health Science Center, Houston,
TX, United States
The effect of lesion in-painting on the estimated
regional atrophy in multiple sclerosis (MS) was
evaluated on a large cohort for different T2 lesion
burdens. The results suggest that in-painting has
effects on regions close to the ventricular regions. The
effect is most prominent at high lesion burden.
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