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Abstract #3444

High Resolution MRI for Functional Evaluation of the Parotid Glands Following Continuous Stimulation.

Evanthia Kousi 1 , Maria Schmidt 1 , Rafal Panek 1 , Marco Borri 1 , Alison MacDonald 1 , Liam Welsh 1 , Angela Riddell 1 , Kate Newbold 2 , and Martin Leach 1

1 CR-UK and EPSRC Cancer Imaging Centre,Institute of Cancer Research, Royal Marsden Hospital, Sutton, Surrey, United Kingdom, 2 Head&Neck Unit, Royal Marsden Hospital, Sutton, Surrey, United Kingdom

In this study, high resolution MRI was performed for the evaluation of the parotid glands function after continuous salivary stimulation on healthy volunteers. ADC and signal intensity on heavily T2-w images were measured before and during continuous stimulation. ADC and image intensity on HT2W images of the parotids increased after stimulation, whereas, a heterogeneous stimulation response of the gland was observed. However, no spatial correspondence was found between ADC and intensity increases in heavy T2-w images. Our results indicate that high resolution images combined with continuous stimulation of parotids is a successful strategy to achieve functional assessment at regional level.

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