Abstract #3446
Differential Motion In Orbital And Global Layers Of Extraocular Muscles Measured By Tagged MRI At 7T
Thomas Stewart Denney Jr 1,2 , Mark Bolding 3,4 , Ronald Beyers 1 , Nouha Salibi 1,5 , Ming Li 1,2 , Xiaoxia Zhang 1,2 , and Paul Gamlin 6
1
AU MRI Research Center, Auburn University,
Auburn, AL, United States,
2
Department
of Electrical and Computer Engineering, Auburn
University, Auburn, AL, United States,
3
Department
of Radiology, University of Alabama Birmingham,
Birmingham, AL, United States,
4
Department
of Vision Sciences, University of Alabama Birmingham,
Birmingham, AL, United States,
5
MR
R&D, Siemens Healthcare, Malvern, PA, United States,
6
Department
of Ophthalmology, University of Alabama Birmingham,
Birmingham, AL, United States
The mechanisms of how extraocular muscles control eye
movements are not well understood, but are important in
developing treatments for strabismus and other eye
motion disorders. Using standard tagged cardiac MRI
sequences and head coils in a 7T scanner, strain was
measured in the orbital and global components of the
right lateral rectus muscle under horizontal saccadic,
horizontal smooth pursuit, and asymmetric convergence
saccadic motions. The orbital and global layers showed
differences in strain for horizontal saccadic eye
movements but not for asymmetric convergence, which
suggests that these layers move relatively independently
and differing amounts for different horizontal eye
movements.
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