Abstract #3471
Measurements of glutamatergic pathway in patients with schizophrenia using 7T MRSI
Yan Li 1 , Angela Jakary 1 , Daniel H Mathalon 2,3 , and Sarah J Nelson 1,4
1
Department of Radiology and Biomedical
Imaging, University of California San Francisco, San
Francisco, California, United States,
2
Department
of Psychiatry, University of California San Francisco,
San Francisco, California, United States,
3
Mental
Health Service, San Francisco Veterans Administration
Medical Center, San Francisco, California, United
States,
4
Department
of Bioengineering and Therapeutic Sciences, university
of California San Francisco, San Francisco, California,
United States
The purpose of this study was to compare the levels of
glutamate, glutamine, γ-aminobutyric acid, glutathione
and glycine in patients with schizophrenia to those in
healthy controls using 3D short-echo MRSI at 7 Tesla.
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