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Abstract #3526

Functional assessment of hypopituitarism: Novel perfusion criteria using radial-VIBE sequence with GRASP technique

Camilla Rossi Espagnet 1 , Lev Bangiyev 1 , Kai Tobias Block 2 , Robert Grimm 3 , Daniel K. Sodickson 2 , Benjamin Cohen 1 , Thomas Mulholland 2 , Ajax George 1 , James Babb 2 , and Girish Fatterpekar 1

1 Neuroradiology, NYULMC, New York, NY, United States, 2 Radiology, NYULMC, New York, NY, United States, 3 Pattern Recognition Lab, FAU, Erlangen, Nuremberg, Germany

Evaluating functional-perfusion information from the pituitary gland when no structural abnormality is present in patients with central endocrinologic symptoms has not been explored. The purpose of our study was therefore to evaluate perfusion parameters using radial VIBE with GRASP in patients with central endocrine disturbances. A retrospective study was performed in 43 patients (Controls: n = 33, and Patients: n = 10). Evaluation of signal-time curves from anterior and posterior pituitary gland demonstrated significantly lower perfusion parameters in the patient population. This pilot study suggests that perfusion parameters are abnormal in patients with endocrinologic disturbances despite a normal appearing gland.

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