Abstract #3551
Pulmonary Ultra-short Echo-time (UTE) Two-dimensional Radial Acquisition with Compressed Sensing: Preliminary Quantitative Results with Comparison to Thoracic CT
Weijing Ma 1 , Khadija Sheikh 1,2 , Jonathon Leipsic 3 , Harvey O Coxson 3 , David G McCormack 4 , Roya Etemad-Rezai 5 , and Grace Parraga 1,2
1
Imaging Research Laboratories, Robarts
Research Institute, London, Ontario, Canada,
2
Department
of Medical Biophysics, The University of Western
Ontario, Ontario, Canada,
3
Department
of Radiology, University of British Columbia, Vancouver,
British Columbia, Canada,
4
Department
of Medicine, The University of Western Ontario, London,
Ontario, Canada,
5
Department
of Medical Imaging, The University of Western Ontario,
London, Ontario, Canada
We developed thoracic 32-channel ultra-short echo time
radial 1H MRI with compressed sensing to achieve
quantitative 1H signal intensity maps on a clinical 3T
scanner for quantitative measurements of the lung
parenchyma. Such measurements were directly compared in
healthy volunteers at different lung volumes and in
patients with COPD and bronchiectasis with 3He MRI
apparent diffusion coefficients, CT measurements of
tissue density and pulmonary function test measurements.
Compressed sensing UTE MRI was successfully implemented
at 3T and showed significantly improved SI measurements
acquired at expiration breath-hold that is safe and
practical for patients with chronic respiratory disease.
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