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Abstract #3584

Interobserver agreement in relative liver lesion signal intensity on hepatobiliary phase imaging with gadoxetic acid (Gd-EOB-DTPA)

Sharon Ngu 1 , Lizza Lebron-Zapata 1 , Christy Pomeranz 1,2 , Seth Katz 1 , Scott Gerst 1 , Michael Sohn 1 , Junting Zheng 3 , Chaya Moskowitz 3 , and Richard K. G. Do 1

1 Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States, 2 New York Presbyterian Hospital - Weill Cornell, New York, New York, United States, 3 Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States

A retrospective study was conducted to assess interobserver agreement in the qualitative and quantitative evaluation of liver lesions signal intensity (SI) on delayed hepatobiliary phase MRI with gadoxetic acid (Gd-EOB-DTPA). In 50 patients, four readers (2 fellows, 2 experts) assessed lesion SI compared to liver on a 4 point scale and measured SI of the lesion and adjacent liver parenchyma. Result showed almost perfect agreement in expert readers and substantial agreement among fellows. A cutoff point of lesion to liver SI ratio of 0.876 was found to differentiate hypointense from iso- to hyperintense liver lesions on delayed hepatobiliary phase.

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