Abstract #3597
Signal Intensity Ratio between Liver and Muscle Reference in Highly Iron Overloaded Patients: comparing 1.5 T to 3 T
Arthur Peter Wunderlich 1 , Steffen Klmpken 1 , Holger Cario 2 , Markus Juchems 1 , and Meinrad Beer 1
1
Dept. for Diagnostic and Interventional
Radiology, Univ.-Clinic Ulm, Ulm, Germany,
2
Pediatry,
Univ.-Clinic Ulm, Ulm, Germany
The liver of highly iron overloaded patients was scanned
with breathhold GRE sequences at 1.5 T and 3 T. To
address high liver iron content (LIC), we measured the
signal intensity ratio (SIR) between liver and
paraspinal muscle serving as reference. In theory,
logarithm of these SIR values are expected to depend
linearly on R
2
* difference between liver and
muscle tissue which itself varies with LIC due to R
2
*
changes with iron deposition in the liver. Dependence of
SIR on LIC was evaluated and results compared between
field strengths.
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