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Abstract #3638

The high negative predictive value to pre-operative MRI in Grade I endometrial cancer in the clinical setting.

Erin Bravo 1 , Krupa Patel-Lippmann 2 , Kristie Guite 3 , Jessica Robbins 3 , David Kushner 2 , Ahmed Al-Niaimi 2 , and Elizabeth Sadowski 2

1 Radiology, University of Wisconsin, Madison, Wisconsin, United States, 2 University of Wisconsin, Wisconsin, United States, 3 Radiology, University of Wisconsin, Wisconsin, United States

In grade 1 endometrial cancer there is debate whether or not lymphadenectomy is necessary. Strong evidence exists that women without myometrial or cervical invasion have decreased risk of lymph node metastasis, thus may potentially avoid lymphadenectomy. The goal of our study was to evaluate myometrial and cervical invasion in women with grade 1 endometrial cancer on preoperative MRI when being read by abdominal radiologists compared with surgical pathology. Our study determined the negative predictive value of MRI in detecting myometrial and/or cervical invasion is 96%, which may decrease the need for lymphadenectomy in women with very low risk for lymph node metastasis.

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