Abstract #3670
Respiratory phase-resolved 3D MRI with isotropic high spatial resolution: Determination of the average breathing motion pattern for abdominal radiotherapy planning
Zhaoyang Fan 1 , Jianing Pang 1,2 , Wensha Yang 1 , Yong Yue 1 , Richard Tuli 1 , Guoxi Xie 1,3 , Xiaoming Bi 4 , Benedick Fraass 1 , and Debiao Li 1
1
Cedars-Sinai Medical Center, Los Angeles,
CA, United States,
2
Northwestern
University, Chicago, IL, United States,
3
Shenzhen
Institutes of Advanced Technology, Shenzhen, Guangdong,
United States,
4
MR
R&D Siemens Healthcare, Los Angeles, CA, United States
Four-dimensional CT is currently a standard in
radiotherapy planning to assess breathing motion and
determine treatment margins for organ tumors. However,
this modality has poor soft-tissue (or tumor) contrast
and involves high radiation dose. These limitations can
be overcome by using 4D MRI. The present work developed
a retrospective 4D MRI technique (respiratory
phase-resolved 3D MRI) that features: a) isotropic high
spatial resolution (1.56 mm), b) a fixed scan time (8
minutes or less), c) an estimate of average respiratory
phase resolved motion pattern with, and d) minimal
intra-phase motion artifact.
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