New MR thermometry approach to follow small temperature variation: in-vivo validation on the anesthetized baboons brain at 7T
Nicolas Boulant 1 , Alexandre Vignaud 1 , Eric Giacomini 1 , Benoit Larrat 1 , Aurelien Massire 1 , Alexis Amadon 1 , Lynn Uhrig 1 , and Michel Bottlaender 1
Neurospin, CEA, Saclay, Ile de France,
Measuring small temperature rises (<1 C) in-vivo using
MR thermometry is a challenging task given the required
stability of the whole transmission-reception chain as
well as the physiological noise spoiling the desired
signal. We here report an experiment performed at 7T
in-vivo on a baboons head where a non-local RF-heat
generating system was separate from the MR scanner to
provide high stability. Navigator free induction decays
were used to correct for the DB0 variations induced by
breathing and for the drift of the external field.
Combined with the proton resonance frequency shift
method, accuracy of ~0.1 C could be obtained.
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