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Abstract #3690

MRI guided percutaneous catheter-based high intensity ultrasound thermal ablation in swine muscle and kidneys.

Ricky Tong 1 , K. Pallav Kolli 1 , Chris Diederich 2 , Vasant Salgaonkar 2 , Viola Rieke 1 , Eugene Ozhinsky 1 , Maythem Saeed 1 , Loi Do 1 , Steve Hetts 1 , and Mark Wilson 1

1 Radiology, UCSF, San Francisco, CA, United States, 2 Radiation Oncology, UCSF, San Francisco, CA, United States

Catheter-based high intensity ultrasound is a novel technology with the potential for precise thermal treatment delivery under real time imaging guidance. The potential advantages of this technology over other ablative therapies include dynamic 3-dimensional spatial control of energy deposition and greater penetration of delivered energy. In this study, a percutaneous MR compatible high intensity ultrasound catheter was used to ablate swine tissues in both ex-vivo and in-vivo settings. MR thermometry enabled us to monitor temperature changes during ablation. MR images defined the ablation site, which was confirmed with gross specimen and histology as irreversible thermal damage.

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