MRI guided percutaneous catheter-based high intensity ultrasound thermal ablation in swine muscle and kidneys.
Ricky Tong 1 , K. Pallav Kolli 1 , Chris Diederich 2 , Vasant Salgaonkar 2 , Viola Rieke 1 , Eugene Ozhinsky 1 , Maythem Saeed 1 , Loi Do 1 , Steve Hetts 1 , and Mark Wilson 1
Radiology, UCSF, San Francisco, CA, United
Oncology, UCSF, San Francisco, CA, United States
Catheter-based high intensity ultrasound is a novel
technology with the potential for precise thermal
treatment delivery under real time imaging guidance. The
potential advantages of this technology over other
ablative therapies include dynamic 3-dimensional spatial
control of energy deposition and greater penetration of
delivered energy. In this study, a percutaneous MR
compatible high intensity ultrasound catheter was used
to ablate swine tissues in both ex-vivo and in-vivo
settings. MR thermometry enabled us to monitor
temperature changes during ablation. MR images defined
the ablation site, which was confirmed with gross
specimen and histology as irreversible thermal damage.
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