Abstract #3830
Interleaved Magnetic Steering and MR imaging of USPIO Particles in One Dimension: Early Results
Hsin-Jung Yang 1 , Ke Cheng 1 , Ryan middleton 1 , Ivan Cokic 1 , Avinash Kali 1 , Louis Bouchard 2 , Eduardo Marban 1 , and Rohan Dharmakumar 1
1
Cedars Sinai Medical Center, Los Angeles,
California, United States,
2
UCLA,
Los Angeles, California, United States
Retention of cells within regions of interest following
their delivery is a known obstacle in the field of
regenerative medicine. Recent studies have demonstrated
that magnetic field gradient of bar magnets can be used
to couple with the dipole moment of the cells labeled
with iron oxide can be used to enhance retention and
therapeutic regeneration. In this work, we investigated
whether a Maxwell coil, which can be positioned within
the MR scanner, would be able to deliver sufficient
one-dimensional force on USPIO particles and the effect
of this resultant force can be captured on the basis of
T2* MRI.
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