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Abstract #3853

Distal cerebral arterial pulsatility using 4D Flow MRI

Anders Whlin 1,2 , Eric Schrauben 1,3 , Oliver Wieben 3 , Khalid Ambarki 1 , Jan Malm 4 , and Anders Eklund 1,5

1 Department of Radiation Sciences, Ume University, Ume, Sweden, 2 Ume Center for Functional Brain Imaging, Ume University, Ume, Sweden, 3 Department of Medical Physics, University of Wisconsin, Madison, WI, United States, 4 Department of Clinical Neuroscience, Ume University, Ume, Sweden, 5 Center for Biomedical Engineering and Physics, Ume University, Sweden

Age related high pulsatility of distal brain arteries is thought to damage exposed brain tissue, leading to brain atrophy and cognitive decline among elderly. Previous studies have focused on assessing central pulsatility or pulsatility in cervical arteries feeding the brain. We show that high-resolution 4D Flow MRI is capable of assessing pulsatility of distal branches of the cerebral arterial circulation, a result that should stimulate research aimed for understanding arterial pulsatility as a contributing factor to dementia.

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