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Abstract #3887

Tissue Phase Mapping Using Single Breath-hold 4D PCMR

Jennifer Anne Steeden 1 , Grzegorz Kowalik 1 , Andrew Taylor 1 , and Vivek Muthurangu 1

1 Centre for Cardiovascular Imaging, UCL Institute of Cardiovascular Science, London, United Kingdom

Magnetic resonance tissue phase mapping (TPM) allows assessment of the separate directional components of wall motion. The purpose of this study was to develop a highly accelerated 4D PCMR sequence (R=8, using SENSE and UNFOLD) to acquire TPM data across the entire left ventricle, during a single breath-hold (of 16 heartbeats). Data was acquired in 5 healthy volunteers and 1 patient. Evidence of dyssynchrony in early LV diastole was seen in the patient, as well as significantly lower longitudinal velocities compared to healthy volunteers. We show that using a novel spiral UNFOLD SENSE PCMR sequence it is possible to obtain 4D TPM data in a single breath-hold.

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