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Abstract #3920

Effect of Rosuvastatin Therapy on the Adventitial Perfusion of Carotid Plaque with Intraplaque Hemorrhage: A Dynamic Contrast-enhanced MR Imaging Study

Jianming Cai 1 , Bao Cui 1 , Ruixue Du 2 , Lu Ma 1 , Xu Han 1 , Youquan Cai 1 , Xin Lou 1 , Lin Ma 1 , and Ping Ye 2

1 Department of Radiology, Chinese PLA General Hospital, Beijing, China, 2 Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China

Evaluation of effects of lipid-lowering therapy on atherosclerotic plaques with IPH should be focused on inflammatory activity rather than composition and plaque burden. IPH may be irreversible content within the first one year after treatment. Kinetic parameters of DCE-MRI has the most possibility to become the valuable biomarker in vivo, noninvasively.

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