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Abstract #4065

High Order Diffusion Tensor Imaging for Breast Cancer Differentiation

Jose Ramon Teruel 1,2 , Hans Erikssnn Fjsne 3,4 , Agnes stlie 5 , Pl Erik Goa 2,6 , and Tone Frost Bathen 1

1 Department of Circulation and Medical Imaging, NTNU, Trondheim, Norway, 2 St. Olavs University Hospital, Trondheim, Norway, 3 Department of Surgery, St. Olavs University Hospital, Trondheim, Norway, 4 Institute of Cancer Research and Molecular Medicine, NTNU, Trondheim, Norway, 5 Department of Radiology, St. Olavs University Hospital, Trondheim, Norway, 6 Department of Physics, NTNU, Trondheim, Norway

In our study we evaluate the potential of a 4th order diffusion tensor imaging (DTI) model for breast cancer differentiation. Our results reveal how this model outperforms standard DTI for differentiation of malignant and benign lesions, and healthy fibroglandular tissue. In particular, fractional anisotropy derived from this model is found to increase the potential of diffusivity markers to differentiate malignant and benign lesions.

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