Abstract #4091
Clinical Implementation of Slice Accelerated EPI-DSC MR Perfusion Weighted Imaging
Donald Robinson Cantrell 1 , Thomas Anthony Gallagher 1 , Bruce Spottiswoode 2 , Timothy Carroll 1,3 , Charles Fasanati 1 , and Dingxin Wang 4,5
1
Department of Radiology, Northwestern
University, Chicago, IL, United States,
2
Cardiovascular
MR R&D, Siemens Healthcare, Chicago, IL, United States,
3
Department
of Biomedical Engineering, Northwestern University,
Chicago, IL, United States,
4
Siemens
Medical Solutions USA, Inc., Minneapolis, MN, United
States,
5
CMRR,
University of Minnesota, Minneapolis, MN, United States
Perfusion Weighted Imaging (PWI) provides functional
information on the hemodynamic status of CNS
malignancies. Dynamic Susceptibility Contrast (DSC)
enhanced MRI is an implementation of PWI that rapidly
acquires images following contrast administration.
However, standard clinical DSC-MRI protocols have
limited spatial coverage and temporal resolution. Our
previous work demonstrated the feasibility of using
Slice Accelerated Echo Planar Imaging (SA-EPI) for
DSC-MRI measurements in healthy volunteers. We now
report the first large-scale clinical implementation of
this promising new protocol for the evaluation of CNS
malignancies. Faster data acquisition achieved with
SA-EPI allows for increased spatial coverage while
maintaining the required temporal resolution.
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