Simultaneously resolve haemodynamic response function and activation response by rank-constrained optimization

A novel technique to concurrently resolve HRF and quantify fMRI activation response is presented. The problem formulation involves a rank 1 constraint (nonconvex), which makes it very difficult to solve. We were able to compute rank minimization by reformulating the nonconvex problem into a sequence of convex problems. We also developed an acceleration method such that computation time (global convergence) is significantly improved. We achieved over 99.9% accuracy on both HRF and stimulation response in simulations using parameters typical to fMRI studies. Our technique can benefit research involving a population having HRF that deviates from the canonical assumption.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.