Abstract #4176
CHARACTERIZATION OF THALAMIC FUNCTIONAL COMPONENTS AND THEIR CONNECTIONS WITH CEREBRAL CORTEX : A DTI AND RS fMRI STUDY
Chiara Mastropasqua 1,2 , Marco Bozzali 1 , Giovanni Giulietti 1 , Giacomo Koch 3 , and Mara Cercignani 1,4
1
Neuroimaging Laboratory, IRCCS Santa Lucia,
Rome, Italy,
2
Trieste
University, Rome, Italy,
3
Department
of Clinical and Behavioural Neurology, IRCCS Santa
Lucia, Rome, Italy,
4
Clinical
Imaging Sciences Centre - University of Sussex, Brighton
and Sussex Medical School, Brighton, United Kingdom
With the aim of comparing thalamo-cortical functional
and structural connections, we used independent
component analysis of resting state (RS) fMRI data to
detect thalamic functional components at rest. Next, we
used these thalamic components as seeds for RS seed
based analysis and probabilistic tractography to
identify cortical regions structurally and functionally
connected with each thalamic components. The results
were visually compared to cross-validate these two
commonly used approaches. These two methods yield
partially consistent results: the partial overall
correspondence between structural and functional
connections suggests that they provide complementary
information.
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