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Abstract #4181

Brain without Anatomy: Construction and Comparison of Fully Network-Driven Diffusion MRI Connectomes

Olga Tymofiyeva 1 , Etay Ziv 1 , Donna M Ferriero 2 , A James Barkovich 1 , Christopher P Hess 1 , and Duan Xu 1

1 Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2 Department of Pediatrics, University of California, San Francisco, San Francisco, CA, United States

Through the abstraction from the anatomy, the developed framework allows for unbiased construction and connection-wise comparison of diffusion MRI-based brain networks. Brain alignment is performed in the network domain and, therefore, can be applied to subjects at any stage of development with any potential anatomical abnormalities.

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