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Abstract #4185

High resolution fMRI reveals laminar specific resting-state functional connectivity in primary somatosensory cortex in non-human primates

Shantanu Majumdar 1,2 , Feng Wang 1,2 , Li Min Chen 1,2 , and John C Gore 1,2

1 Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, 2 Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States

The study of inter-laminar functional connectivity within the primary somatosensory (S1) cortex provides great depth of knowledge about input and output information process in S1 cortex for somatic sensation, but few studies have resolved the contributions of different cortical layers to measured BOLD signals. In this work, we performed sub-millimeter resolution resting-state functional MRI in the S1 cortex in anesthetized squirrel monkeys and examined the laminar specific functional connectivity between sub-regions (area 3a, area 3b and area 1) of the S1 cortex.

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