Investigating the field-dependence of the Davis model: Calibrated fMRI at 1.5, 3 and 7 tesla

Calibrated functional MRI (fMRI) is most often performed at 3T, but there is increasing interest in implementing this method on 7T research and 1.5T clinical systems. It is currently unclear whether this affects the accuracy of the resultant measurements of oxygen metabolism. We investigated the robustness of such measurements by performing the same calibrated fMRI protocol at 1.5, 3 and 7T. The calibration parameter M was found to increase predictably with field strength, whilst the estimated change in oxygen metabolism in response to a motor task was independent of field strength.

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