Selective Imaging of Bound Water in Cortical Bone with Inversion Recovery Prepared Ultrashort Echo Time Sequences

Bone water occurs at various locations and in different binding states. In normal bone the majority of bone water is loosely bound to the organic matrix. There is also a significant amount of free water residing in the pores of bone which is responsible for nutrient diffusion and contributes to the viscoelastic properties of cortical bone. Separation of bound water from free water is of critical importance since the two make different contributions to the mechanical properties of bone. In this study we aimed to investigate the effects of inversion time (TI) on bone free water signal using an adiabatic inversion recovery prepared ultrashort echo time (IR-UTE) sequence on a clinical whole body 3T scanner.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.