Abstract #4276
On the need for T2* correction in quantitative water-fat imaging of skeletal muscle
Dimitrios C Karampinos 1 , Stefan Ruschke 1 , Holger Eggers 2 , Marcus Settles 1 , Hendrik Kooijman 3 , Peter Brnert 2 , Ernst J Rummeny 1 , and Thomas Baum 1
1
Department of Diagnostic and Interventional
Radiology, Technische Universitt Mnchen, Munich,
Germany,
2
Philips
Research Laboratory, Hamburg, Germany,
3
Philips
Healthcare, Hamburg, Germany
It is known that T
2
* decay effects can induce
significant bias in the estimation of the fat fraction
using a chemical shift based water-fat separation
methods, especially in the presence of short T
2
*.
However, the need for T
2
* correction has not
been previously characterized in skeletal muscle fat
quantification, where T
2
* decay is moderate
but susceptibility-induced fat resonance shift effects
are also present. The present study shows the existence
of a synergistic effect between T
2
* decay and
susceptibility shift on the estimation of the fat
fraction. Single T
2
* correction reduces fat
fraction bias due to the synergistic effect of T
2
*
decay and susceptibility shift, independent of the
choice of TEs.
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