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Abstract #4282

Fast variable inversion-recovery time EPI for anatomical reference and quantitative T 1 mapping

Ville Renvall 1,2 , Thomas Witzel 1,2 , Lawrence L. Wald 1,2 , and Jonathan R. Polimeni 1,2

1 Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2 Department of Radiology, Harvard Medical School, Boston, MA, United States

Fast T 1 mapping method using permuted slice acquisition order and TI skipping on an IR EPI scan was developed. The resulting T 1 and T 2 * / spin density images were used to synthesize inversion recovery EPI data with an arbitrary, selectable TI. Automatic brain segmentation and cortical surface reconstruction of the synthesized data using FreeSurfer were successful and could serve as basis for distortion matched anatomical reference for functional MRI.

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