Computing average cortical profiles at 3 Tesla

Numerous cortical thickness studies using MRI operating at conventional field strengths (e.g. 3T) showed cortical reductions for various psychiatric diseases. But the question of which of the cortical layers were implicated could not be answered. Here we propose an automatic method that can extract additional cortical information from MRI scans acquired at conventional field strength. Initial experiments indicate that the method yields robust results and that it can be applied in large cohort studies to extract more detailed cortical information.

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