Computing average cortical profiles at 3 Tesla
Rene C. W. Mandl 1 , Martijn P. van den Heuvel 1 , Rachel M. Brouwer 1 , and Hilleke E. Hulshoff Pol 1
Psychiatry, Brain Center Rudolf Magnus, UMC
Utrecht, Utrecht, Utrecht, Netherlands
Numerous cortical thickness studies using MRI operating
at conventional field strengths (e.g. 3T) showed
cortical reductions for various psychiatric diseases.
But the question of which of the cortical layers were
implicated could not be answered. Here we propose an
automatic method that can extract additional cortical
information from MRI scans acquired at conventional
field strength. Initial experiments indicate that the
method yields robust results and that it can be applied
in large cohort studies to extract more detailed
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