Motion artefact correction in quantitative MRI (qMRI) by linear relaxometry modelling

Quantitative MRI (qMRI) with high resolution and whole brain coverage is sensitive to motion artefacts because of typically long acquisition times. We used a multi-parameter mapping (MPM) protocol to acquire quantitative maps of longitudinal relaxation rate (R1), magnetisation transfer (MT) and effective transverse relaxation rate (R2*). These quantitative maps were combined in a linear relaxometry model to reduce motion artefacts by exploiting the inconsistent manifestation of the artefacts across the maps.

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