Abstract #4353
Optimizing Navigator Flip Angle for Free-Breathing Fat-Fraction and R2* Quantification of the Liver
James H. Holmes 1 , Diego Hernando 2 , Yuji Iwadate 3 , Ann Shimakawa 4 , Gavin Hamilton 5 , Utaroh Motosugi 2 , and Scott B Reeder 2,6
1
Global MR Applications and Workflow, GE
Healthcare, Madison, WI, United States,
2
Radiology,
Univeristy of Wisconsin-Madison, Madison, WI, United
States,
3
Global MR Applications and Workflow,
GE Healthcare, Hino, Tokyo, Japan,
4
Global
MR Applications and Workflow, GE Healthcare, Menlo Park,
CA, United States,
5
Radiology,
University of California San Diego, San Diego, CA,
United States,
6
Medical
Physics, University of Wisconsin-Madison, Madison, WI,
United States
Fat and R2* quantification methods, in combination with
free-breathing navigator-based methods provide a
significant advantage for accommodating patients by
removing the need for breath-holding. A trade-off exists
between high signal for navigator motion detection and
high steady-state signal for imaging without introducing
T1 bias. This work evaluates the measured fat-fraction
and R2* as a function of navigator flip angle. Results
suggest the navigator excitation flip angle should be 10
degrees or lower to minimize fat-fraction bias at the
location of the navigator excitation and enable
fat-fraction and R2* measurements in good agreement with
stationary phantoms.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
