Abstract #4359
Achieving 3D CINE from free breathing multi-slice 2D acquisitions via Simultaneous Groupwise Manifold Alignment
Muhammad Usman 1 , Christian Baumgartner 1 , Andrew King 1 , David Atkinson 2 , Tobias Schaeffter 1 , and Claudia Prieto 1,3
1
Division of Imaging Sciences and Biomedical
Engineering, King's College London, London, Greater
London, United Kingdom,
2
Department
of Image Computing, University College London, London,
United Kingdom,
3
Escuela
de Ingenieria, Pontificia Universidad Catolica de Chile,
Santiago, Chile
Multislice 2D CINE MRI is a common approach for
assessing cardiac function and anatomy. This approach
requires multiple breath-holds and usually suffers from
slice-misalignments due to motion between the
acquisitions. To overcome these problems, free-breathing
respiratory-gated 3D CINE MRI have been proposed.
However, these methods require long acquisition times
and suffer from poorer contrast between blood and
myocardium than 2D acquisitions1. In this work, we
propose to combine the contrast of 2D acquisitions with
the coverage of the 3D scans by generating a simulated
3D scan. This is achieved by addressing the issue of
misalignment, which can occur between different slices
in a multi-slice acquisition, using a self-gated
Simultaneous Groupwise Manifold Alignment (SGA)
technique. Prospective golden radial cardiac MR
acquisitions, performed in 3 volunteers, demonstrate the
feasibility of proposed framework to achieve gated
simulated 3D CINE from free-breathing multi-slice 2D
acquisitions.
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