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Abstract #4367

Very Rapid 4D Compressed Sensing MR for Lung Imaging during Forced Expiration

Benjamin Paul Berman 1 , Abhishek Pandey 2 , Zhitao Li 2 , Theodore Trouard 3,4 , Isabel Oliva 4 , Diego R. Martin 4 , Maria Altbach 4 , and Ali Bilgin 2,3

1 Applied Mathematics, University of Arizona, Tucson, Arizona, United States, 2 Electrical and Computer Engineering, University of Arizona, Tucson, Arizona, United States, 3 Biomedical Engineering, University of Arizona, Tucson, Arizona, United States, 4 Medical Imaging, University of Arizona, Tucson, Arizona, United States

Spirometry measurements during expiration are standard for diagnosis of many lung diseases. However, these measurements contain no spatial information. Highly accelerated 4D MRI with compressed sensing can be used to image the lungs during forced respiratory maneuvers. Golden angle stack-of-stars view ordering is utilized to distribute the data into undersampled temporal bins. Total variation between neighboring frames, as well as reference frames acquired during the same scan, provide enough sparsity to reconstruct images with as few as 1 readout per slice per time, ie. 100x acceleration, ie. 46ms resolution.

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