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Abstract #4379

Toward Robust, Clinically-Practical Single-Breathhold 3D Cardiac Cine MRI with High Acceleration and Rapid Online Reconstruction

Peng Lai 1 , Shreyas S Vasanawala 2 , and Anja CS Brau 3

1 Global MR Applications & Workflow, GE Healthcare, Menlo Park, CA, United States, 2 Radiology, Stanford University, Stanford, CA, United States, 3 Global MR Applications & Workflow, GE Healthcare, Munich, Germany

3D cine MRI with high spatiotemporal resolution remains challenging due to residual artifacts and temporal flickering. Reconstruction for k-t accelerated 3D cine with high-density coil poses high computation demand, which is difficult for online processing. This work developed a new variable-density random k-t sampling scheme that produces less-disturbing noise-like artifacts and can be further suppressed by denoising. Also, this work combines a few newly developed algorithms (e.g. coil compression and data decoupling calibration) to address the computation challenge. The proposed sampling scheme and reconstruction framework improves the robustness of 3D cine with 9x acceleration and enables rapid online processing.

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