Abstract #4412
Probing the vitality of yeast suspensions by Double Diffusion Weighted MRI
Lars Mueller 1 , Andreas Wetscherek 1 , Jutta Janke 1 , Bram Stieltjes 2 , and Frederik Bernd Laun 1
1
Medical Physics in Radiology, German Cancer
Research Center, Heidelberg, Germany,
2
Quantitative
Imaging-based Disease Characterization, German Cancer
Research Center, Heidelberg, Germany
A double diffusion weighted sequence was implemented and
tested on yeast suspension phantoms with different yeast
concentrations. The sequence allowed us to determine the
apparent exchange rate, which is a measure for water
exchange rates across cell membranes, and the filter
efficiency. Higher yeast concentrations result in lower
exchange rates and higher filter efficiencies. Both
parameters are dependent on the age of the yeast
suspension and are shown to be good indicators of the
vitality of the yeast suspension.
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