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Abstract #4445

Self-feeding MUSE: A Method for High Resolution Diffusion Weighted Imaging with Robust Phase Variation Estimation

Zhe Zhang 1 , Feng Huang 2 , Bida Zhang 3 , Sheng Fang 4 , and Hua Guo 1

1 Center for Biomedical Imaging Research, Department of Biomedical Enginnering, School of Medicine, Tsinghua University, Beijing, China, 2 Philips Healthcare, Gainesville, FL, United States, 3 Philips Research China, Beijing, China, 4 Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing, China

Multi-shot strategies have been used for improving spatial resolution of DWI. MUSE is a multi-shot EPI based DWI method using SENSE for self-navigating of each shot. When many shots are used to decrease the EPI distortion and blurring, high SENSE reduction factor will cause inaccurate phase estimation and thus ghost artifacts. In this work, Self-feeding MUSE is proposed for robust phase estimation and improved MUSE reconstruction, even if the number of shots is high.

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