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Abstract #4479

Comparison of the accuracy between manual and computerized anatomical delineation techniques in ex-vivo diffusion tensor imaging of the mouse brain.

Hedok Lee 1,2 , Joe Cavallo 1 , Vivek Goyal 1 , Sagar Dhandia 1 , Michael Cutrone 1 , Elyssa Chen 1 , Tian Fang 1 , Helene Benveniste 1,2 , and Thomas Floyd 1,2

1 Anesthesiology, State University of New York at Stony Brook, Stony Brook, New York, United States, 2 Radiology, State University of New York at Stony Brook, Stony Brook, New York, United States

In this study we compared manual and semi-automated computerized anatomical delineation techniques in ex-vivo diffusion tensor imaging of the mouse brain. The accuracy of both FAs and anatomical volumes in the computerized technique was comparable or just below the discrepancies caused by subjective bias between the two raters. We conclude that the computerized method is effective and time efficient method in analyzing FA and anatomical volumes.

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