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Abstract #4508

Probabilistic mapping of brain connectivity in the IIT Human Brain Atlas

Anna Varentsova 1 , Shengwei Zhang 2 , and Konstantinos Arfanakis 2,3

1 Department of Physics, Illinois Institute of Technology, Chicago, IL, United States, 2 Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, United States, 3 Rush Alzheimer's Disease Center, Rush University, Chicago, IL, United States

The IIT Human Brain Atlas project is in the 4th year of development (www.nitrc.org/projects/iit2). The latest version of the atlas contains high-quality artifact-free anatomical, DTI, HARDI templates, and probabilistic gray matter (GM) labels of the adult human brain in ICBM-152 space. The project is currently focusing on the development of a probabilistic white matter atlas that is complementary to the GM atlas, by performing tractography in the state-of-the-art HARDI template using the labels of the GM atlas as seeds. The present work aimed to: a) evaluate the tractography results, and b) generate probabilistic connectivity maps for pairs of GM labels.

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