Abstract #4527
Evaluation of diffusion acquisition and tractography methods for neurosurgical planning systems
Jonathan Ashmore 1 , Flavio Dell'Acqua 2 , Ruth O'Gorman 3 , Gareth Barker 2 , and Jozef Jarosz 1
1
Neuroradiology, Kings College Hospital,
London, United Kingdom,
2
Department
of Neuroimaging, Kings College London, London, United
Kingdom,
3
University
Children's Hospital, Zurich, Switzerland
The purpose of this study was to investigate how
diffusion acquisition parameters including the number of
diffusion directions, the use of cardiac gating and the
use of non-isotropic versus isotropic voxels impacts on
tractography of the corticospinal tract for application
to neurosurgical planning. We consider the tractography
generated from a regulatory approved neurosurgical
planning system to those produced from research software
which incorporates constrained spherical deconvolution
and probabilistic tractography. All tractography results
are assessed against cyctoarchitectonic maps of the
corticospinal tract which is used as a gold standard to
asses the validity of the generated tracts.
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