Abstract #4541
Sensitivity and specificity of prostate tumor discrimination by IVIM approximation
Gina Belmonte 1 , Vito Biondo 2 , Augusto La Penna 3 , Francesco Carbone 4 , Gianluca Vischi 5 , Leonardo Semeraro 5 , and Fabrizio Banci Buonamici 1
1
Medical Physics, University Hospital of
Siena, Siena, Italy, Italy,
2
University
of Siena, Italy, Italy,
3
Radiology,
University of Siena, Italy, Italy,
4
Radiology,
University Hospital of Siena, Italy, Italy,
5
Radioterapy,
University of Siena, Italy, Italy
We analyzed precision and accuracy in the discrimination
of prostate tumor of IVIM parameters measured with a
bi-exponential fit and a simplified approach, that
allows to estimate the diffusion coefficient and the
pseudo-diffusion fraction from a 2 b-values acquisition.
ROC analysis were used to extract the optimum cut-off
for each parameter that maximize the accuracy of test.
The simplified IVIM parameters are not accurate
estimates of the corresponding ones from the
bi-exponential fit, but discriminate prostate tumor from
healthy tissues in a accurate way. This simplified
technique allows therefore to reduce the acquisition
time and preserve a good diagnostic accuracy.
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