Abstract #4572
A Standardization Phantom for Quantitative Perfusion with Arterial Spin Labeling
Randall B Stafford 1,2 , Michael C Langham 1 , Scott V Davis 3 , Jongho Lee 1,2 , and John A Detre 2,4
1
Radiology, University of Pennsylvania,
Philadelphia, PA, United States,
2
Center
for Functional Neuroimaging, University of Pennsylvania,
Philadelphia, PA, United States,
3
Psychiatry,
Duke University, NC, United States,
4
Neurology,
University of Pennsylvania, Philadelphia, PA, United
States
The purpose of this work is to develop a standardization
phantom for quantitative perfusion with arterial spin
labeling. A two-chamber phantom was constructed
consisting of glass beads and synthetic fiber mesh . The
phantom was tested using pCASL labeling with a
FLASH-based readout at various post-label delays and
flow rates. As expected, increasing the flow rate
resulted in corresponding increases in the percent
difference images. Such a phantom could be used for QA
and sequence standardization across ASL sequences,
vendors, and sites.
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