Abstract #4574
Arterial Compliance of the Middle Cerebral Artery Measured with Short Inversion Time Pulsed Arterial Spin Labelling
Esther A.H. Warnert 1 , Judith E. Hall 2 , and Richard G. Wise 1
1
CUBRIC. School of Psychology, Cardiff
University, Cardiff, United Kingdom,
2
Department
of Anaesthetics and Intensive Care Medicine, School of
Medicine, Cardiff University, United Kingdom
We investigate the possibility of using pulsed arterial
spin labelling (PASL) to asses intracranial arterial
compliance, a potential marker of cerebrovascular
disease. To do so, we have acquired short inversion time
PASL images (TI < 900ms) and retrospectively grouped
these into systolic and diastolic phases of the cardiac
cycle. Changes in arterial blood volume are calculated
whilst taking the differences between label kinetics in
systole and diastole into account that arise due to
pulsatility of blood flow. Our results indicate that
short inversion time PASL has the potential to assess
arterial compliance of cerebral blood vessels.
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