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Abstract #4669

Characterizing spatial-temporal patterns of neonatal brain development using volume-surface analysis

Yajing Zhang 1 , Michael I. Miller 1 , Linda Chang 2 , and Kenichi Oishi 3

1 Center for Imaging Science, Johns Hopkins University, Baltimore, MD, United States, 2 Department of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, United States, 3 Department of Radiology, Johns Hopkins School of Medicine, Baltimore, MD, United States

Many neurological diseases and functional defects in infants are correlated with abnormal development of specific cortical regions. Therefore, it is important to monitor neonatal cortical development using quantitative tools. We proposed a volume-surface analysis tool based on diffeomorphic mapping technique, and provide informative location-based measures on longitudinal data for characterizing the spatial-temporal growth patterns in the neonatal population.

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